Effect of NMN on DSS Induced Ulcerative Colitis in Mice

Time: 2024-04

Abstract:   Objective To investigate the effects of Nicotinamide mononucleotide (NMN) on ulcerative colitis induced by dextran sulfate sodium (DSS) in mice.  Methods  DSS-induced ulcerative colitis mice were used to evaluate the effects of NMN. After NMN administration, the survival time, weight, disease activit. ndex (DAI), colon tissue length and pathological changes of colon tissue slices were observed.  Results NMN did not cause significant changes in the survival time, weight, DAI, and intestinal morphology of ulcerative colitis mice.  Conclusion  NMN has no significant effect on DSS-induced ulcerative colitis mice.

[Key words] nicotinamide mononucleotide; ulcerative colitis.


doi: 10.12206/j.issn.1006-0111.202006077

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