What is NMN? Read More On Ingredients & NMN Supplements

Time: 2024-03

Learn more about Nicotinamide mononucleotide (NMN) from Uthever

Dr. David Sinclair, a renowned Harvard Medical School professor recognised for his advocacy of resveratrol as a dietary supplement for combating ageing, highly endorses NMN. He incorporates NMN into his daily routine, emphasising its significance for DNA repair, anti-aging benefits, and promoting longevity. Learn more about what the meaning of NMN is, its benefits and why Dr. Sinclair thinks so highly of it.

What is NMN?

Nicotinamide mononucleotide, or NMN, is a naturally occurring molecule found in all living cells. It belongs to a group of molecules called nucleotides, which are the building blocks of RNA and DNA. Structurally, NMN consists of a phosphate group, a ribose sugar, and a nicotinamide base. When consumed, NMN is converted into nicotinamide adenine dinucleotide (NAD+), which helps elevate NAD+ levels. Due to its ability to boost NAD+, NMN is often referred to as an NAD+ booster.

Benefits of NMN

1. Combats Metabolic Disorders

NAD+ plays a crucial role in maintaining healthy mitochondrial function and steady energy output. Unfortunately, ageing and high-fat diets can deplete NAD+ levels in the body. Studies have shown that NAD+ boosters can help alleviate weight gain associated with diet and age in mice. They have also shown potential in reversing the effects of diabetes in female mice, offering new strategies to combat metabolic disorders like obesity.

2. Protects Heart Function

Elevating NAD+ levels can protect the heart and improve cardiac function. High blood pressure can lead to an enlarged heart and blocked arteries, increasing the risk of strokes. NAD+ boosters have been found to replenish NAD+ levels in the heart and prevent heart injuries caused by reduced blood flow. Additionally, these boosters have shown the ability to safeguard mice from abnormal heart enlargement.

3. Defends Against Neurodegeneration

Raising NAD+ levels in mice with Alzheimer’s disease has shown promise in reducing protein build-up that disrupts brain cell communication, leading to improved cognitive function. Boosting NAD+ levels also protects brain cells from dying due to inadequate blood flow. Several animal studies highlight the potential of maintaining healthy brain ageing, defending against neurodegeneration, and enhancing memory.

4. Regulating the Immune System

As individuals age, their immune systems tend to decline, making them more susceptible to illnesses and making recovery more challenging. Recent research suggests that NAD+ levels play a crucial role in regulating inflammation and cell survival during the immune response and ageing. This research underscores the therapeutic potential of NAD+ in addressing immune dysfunction.

How is NMN made by the human body?

NMN is produced from B vitamins within the body. The enzyme responsible for NMN synthesis is called nicotinamide phosphoribosyltransferase (NAMPT). NAMPT attaches nicotinamide (a vitamin B3) to a sugar-phosphate called PRPP (5’-phosphoribosyl-1-pyrophosphate). Additionally, NMN can be produced from “nicotinamide riboside” (NR) through the addition of a phosphate group.

NAMPT is a rate-limiting enzyme in NAD+ production. Lower levels of NAMPT result in reduced NMN production, leading to decreased NAD+ levels. Supplementation with precursor molecules like NMN can help speed up NAD+ production.

How are NMN supplements absorbed and used by the human body?

NMN appears to be efficiently absorbed into cells through a molecular transporter embedded in the cell surface. Due to its smaller size compared to NAD+, the NMN molecule may be absorbed more readily into cells. Unlike NAD+, which struggles to pass through the cell membrane, NMN can enter cells directly through an NMN-specific transporter present in the cellular membrane.

Moreover, injections of NMN have been shown to increase NAD+ levels in various regions of the body, including the pancreas, fat tissue, heart, skeletal muscle, kidneys, testes, eyes, and blood vessels. Oral administration of NMN in mice has been found to increase NAD+ levels in the liver within just 15 minutes.

NMN ingredients: How does Uthever make high-purity and high-quality NMN?

NMN supplements are typically produced through chemical or enzymatic synthesis or fermentation biosynthesis.

Chemical synthesis offers advantages from the manufacturer’s perspective, as it allows for mass production of NMN with controlled ingredients and high yield. Uthever® by Effepharm follows the strict guidelines of the United States Pharmacopeia (USP) and the U.S. Food and Drug Administration (FDA) to ensure 100% quality. We work with a renowned international third-party laboratory, Intertek, to confirm the high purity of Uthever® with minimal impurities and endotoxins.

As a result, Uthever® from Effepharm is widely recognised for having the highest purity in the market, making it a preferred choice among buyers in the United States and Europe.

Improve your Health with NMN

Ready to enhance your health? Discover the benefits of NMN supplementation and unlock your potential with Uthever® NMN supplements. Elevate your NAD+ levels, support metabolic health, boost heart function, and fortify your immune system. Trust Uthever® for high-purity and high-quality NMN supplements backed by rigorous testing and scientific research. For more information, check out our NMN studies and learn more about NMN.

Take a step towards better health and vitality. Visit our website to explore our range of NMN supplements and make your purchase today.